Study: Cannabis Could Represent an Effective and Well-Tolerated Treatment for Epileptic Seizures

According to a new study published by Epilepsia Open, “cannabis could actually represent an effective, well-tolerated antiepileptic drug”.

“Cannabidivarin (CBDV) and cannabidiol (CBD) have recently emerged among cannabinoids for their potential antiepileptic properties, as shown in several animal models”, states the study’s abstract. “We report the case of a patient affected by symptomatic partial epilepsy who used cannabis as self-medication after the failure of countless pharmacological/surgical treatments.”

Clinical and video electroencephalogram (EEG) evaluations were periodically performed, and the serum levels of CBDV, CBD, and Δ9-tetrahydrocannabinol were repeatedly measured. After cannabis administration, “a dramatic clinical improvement, in terms of both decrease in seizure frequency and recovery of cognitive functions, was observed, which might parallel high CBDV plasma concentrations.”

To widen the spectrum of CBDV possible mechanisms of action, “electrophysiological methods were applied to investigate whether it could exert some effects on γ-aminobutyric acid (GABA)A receptors.”

According to the study; “Our experiments showed that, in human hippocampal tissues of four patients affected by drug-resistant temporal lobe epilepsy (TLE) transplanted in Xenopus oocytes, there is decrease of current rundown (i.e., reduction of use-dependent GABAA current) after prolonged exposure to CBDV. This result has been confirmed using a single case of Rasmussen encephalitis (RE).”

They conclude by stating that; “Our

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South Carolina Senate Committee Approves Medical Marijuana Bill

South Carolina’s Senate Medical Affairs Committee approved a medical marijuana bill on Thursday, sending it to the full Senate for consideration.

The South Carolina Compassionate Care Act (Senate Bill 212), would allow seriously ill patients to use marijuana to treat their conditions with a recommendation from their doctors.

“There are thousands of South Carolinians who are suffering from serious illness and they’ve already waited far too long,” said Janel Ralph, executive director of Compassionate South Carolina, whose eight-year-old daughter has a rare seizure disorder. “A large majority of voters want to see a compassionate medical cannabis law pass and lawmakers should remain focused on this issue. It isn’t going away. We hope the Senate will take up the measure for a floor vote without further delay, so that patients may finally have relief,” said Ralph.

Despite the progress made by the legislation in the Senate, advocates are concerned the bill will not move far enough through the legislature to get a floor vote in both chambers before the session ends. The House has declined to hear its own medical marijuana bill so far this year, and the deadline for it to advance is April 10.

Supporters of the bill are also upset

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Industrial Hemp Bill Passed by Kansas Legislature

Kansas’ full House of Representatives has given approval to legislation allowing hemp to be legally cultivated (the bill’s already passed the Senate).

The Kansas House of Representatives voted 123 to 1 today to approve Senate Bill 263. The vote comes roughly a month after the Senate passed the measure 36 to 3. Given the measure was amended slightly in the House, it will need to receive one more vote in the Senate before it can be sent to Governor Jeff Colyer for consideration.

The legislation, titled the  Alternative Crop Research Act, would alter the definition of “marijuana” under the state’s controlled substances law to exclude “industrial hemp”. The measure would allow the Kansas Department of Agriculture to cultivate and promote the research and development of industrial hemp. The Department would be given the choice of growing and researching the plant on their own accord, or they could coordinate with a college or university. Individual farmers would also be allowed to grow hemp under supervision of the Department.

Senate Bill 263 would require the Department to promulgate rules and regulations for hemp cultivation by December 31 of this year.

The full text of the bill can be found by clicking here.

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Study: Cannabis has Therapeutic Potential in the Treatment of Alzheimer’s Disease

Cannabis may provide a potential treatment option for those with Alzheimer’s disease, states a new study published by the journal Neurochemical Research.

“Here we demonstrate for the first time that cannabidiol (CBD) acts to protect synaptic plasticity in an in vitro model of Alzheimer’s disease (AD)”, begins the study’s abstract. “The non-psycho active component of Cannabis sativa, CBD has previously been shown to protect against the neurotoxic effects of beta amyloid peptide (Aβ) in cell culture and cognitive behavioural models of neurodegeneration. Hippocampal long-term potentiation (LTP) is an activity dependent increase in synaptic efficacy often used to study cellular mechanisms related to memory.”

Here, researchers “show that acute application of soluble oligomeric beta amyloid peptide (Aβ1-42) associated with AD, attenuates LTP in the CA1 region of hippocampal slices from C57Bl/6 mice. Application of CBD alone did not alter LTP, however pre-treatment of slices with CBD rescued the Aβ1-42 mediated deficit in LTP.” The study found “that the neuroprotective effects of CBD were not reversed by WAY100635, ZM241385 or AM251, demonstrating a lack of involvement of 5HT1A, adenosine (A2A) or Cannabinoid type 1 (CB1) receptors respectively. However in the presence of the PPARγ antagonist GW9662 the neuroprotective effect of CBD was prevented.”

Researchers conclude; “Our data

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Treating Epilepsy: One Family’s Journey with Medical Cannabis

With cannabis now firmly in the spotlight, it’s acceptance as use as a medicine is becoming far more common, and it’s not at all surprising.  Medical marijuana has shown time and time again to have amazing effects for patients battling all types of health conditions, from back pain to epilepsy and everything in between.  The negative stigma surrounding this ancient medicine is finally starting to reverse and cannabis is being recognized for it’s wonderful medicinal properties.  There are countless stories of people, who thought they were beyond hope of living a comfortable life, finding themselves back on their feet after discovering the health benefits of medical cannabis.

Logan Cruickshank 

One such story introduced us to the Cruickshank family of St. Thomas, Ontario.  Therese and Tage Cruickshank are the parents of a lovely boy named Logan, who was diagnosed with Cerebral Palsy when he was less than a year old.  His parents noticed that as a baby, Logan would continually clench his right hand, prompting them to have tests done through their pediatrician.  When the test results came back, they weren’t good.  The family was devastated to discover Logan’s condition, and were in disbelief when told that he would require

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